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If you get any aspect effects, talk with your physician or pharmacist. This incorporates any achievable aspect effects not stated in this leaflet. See segment four.

Codeine phosphate is usually a centrally Energetic analgesic. When administered parenterally, one hundred twenty mg of codeine phosphate produces an analgesic reaction similar to that from 10 mg of morphine. Other actions incorporate respiratory depression; despair from the cough Heart; launch of antidiuretic hormone; activation in the vomiting Heart; pupillary constriction; a lower in gastric, pancreatic, and biliary secretion; a reduction in intestinal motility; an increase in biliary tract stress; and an elevated amplitude of ureteral contractions.

Acetaminophen and codeine phosphate tablets are contraindicated for article-operative management in pediatric sufferers younger than 18 a long time of age following tonsillectomy and/or adenoidectomy[see Contraindications]. •

Acetaminophen and codeine phosphate tablets shouldn't be employed for an extended stretch of time Except if the soreness continues to be serious plenty of to call for an opioid analgesic and for which alternative cure alternatives carry on to generally be inadequate.

If a CYP3A4 inhibitor is discontinued, look at escalating the acetaminophen and codeine phosphate tablets dosage until finally secure drug effects are attained. Consider for signs of opioid withdrawal.

Talk to your health practitioner Should your ache or diarrhoea is just not relieved by the dose of codeine prescribed read more in your case, or if facet effects bother you or will not go away.

These effects appear to improve Using the duration of therapy. The medical importance of these results is not really acknowledged.

A number of other medicines may perhaps change the blood amounts of codeine. Convey to your healthcare supplier about all medicines which you take or have recently taken.

If concomitant use is warranted Appraise people for indications of urinary retention or diminished gastric motility when acetaminophen and codeine phosphate tablets are utilised concomitantly with anticholinergic medications.

you might have taken it according to the Guidelines presented with the prescriber or in the knowledge furnished Along with the medicine and

Codeine sulfate was not mutagenic during the in vitro bacterial reverse mutation assay or clastogenic from the in vitro Chinese hamster ovary mobile chromosome aberration assay.

Will get more info not out of the blue cease taking this medication. If you'd like to cease taking this medication, discuss this with all your prescriber to start with. They are going to show you how To accomplish this, generally by lessening the dose progressively to ensure any uncomfortable withdrawal effects are saved to some minimal.

Suggest patients having acetaminophen and codeine phosphate tablets not to implement MAOIs or in 14 days of halting these procedure. If urgent utilization of an opioid is necessary, use take a look at doses and Recurrent titration of tiny doses of other opioids (like oxycodone, hydrocodone, oxymorphone, hydrocodone, or buprenorphine) to deal with agony while carefully monitoring hypertension and indicators and indicators of CNS and respiratory depression.

Teach people and caregivers on how to acknowledge respiratory despair and emphasize the importance of calling 911 or having unexpected emergency professional medical help without delay within the party of the recognised or suspected overdose [see Warnings, Daily life Threatening Respiratory Despair]. Accidental Ingestion